One anhydrous form also proved to be amorphous, which shifted the focus of this study from polymorphism to amorphism. The research promises to shed new light on the chemical and physical effects that control crystal morphology, polymorphism, allotropy, amorphism, chirality, defects, and twinning, as well as the influence of additives, impurities, and container surfaces, to name but a few. Amorphism and polymorphism of azithromycin . POLYMORPHISM • Polymorphisms of human genes occur at one or more of the following 18. PHARM.) Thesis (PhD (Pharmaceutics))--North-West University, Potchefstroom Campus, 2013Azithromycin, an azalide and member of the macrolide group, is a broad spectrum antimicrobial, representing one of the bestselling antimicrobials worldwide. TYPES OF POLYMORPHISMS SINGLE NUCLEOTIDE POLYMORPHISMS (SNP) • The most common form of polymorphisms is the single nucleotide polymorphism, which is a change in a single base pair (bp) in the genomic DNA. Polymorphism in materials science is the skill of a solid material to exist in more than one form or crystal structure. Polymorphism, pseudopolymorphism, and amorphism of hexakis(2,3,6-tri-O-acetyl)-α-cyclodextrin (TAαCyD), heptakis(2,3,6-tri-O-acetyl)-β-cyclodextrin (TAβCyD), and octakis(2,3,6-tri-O-acetyl)-γ-cyclodextrin (TAγCyD) were investigated using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), powder X-ray diffractometry (XRPD), Fourier transform infrared … Structural elucidation of six of these forms, in addition to the two previously known forms, makes FFA indisputably octamorphic. Low serum levels for the stable polymorph A were observed. Nine polymorphs were accessed through the use of polymer-induced heteronucleation (PIHn) and solid-solid transformation at low temperature. By Roelf Willem Odendaal. What is Polymorphism. An amorphous glassy azithromycin was subsequently prepared and fully characterised to present its solid state profile. Stable form- A, metastable form- B, unstable form- C Form B dissolves faster than form A, and has a much higher solubility. Amorphism and polymorphism of azithromycin ROELF WILLEM ODENDAAL (M.Sc, B. Aucamp Polymorphism of several drugs 12/15/2017 13 Drug Polymorphism aspects Bioavailability issues Chloramphenic ol palmitate Exist in 3 polymorphic forms (A,B,C). Polymorphism, pseudopolymorphism, and amorphism of peracetylated α-, β-, and γ-cyclodextrins July 2006 Journal of Pharmaceutical and Biomedical Analysis 41(4):1205-11 Thesis submitted in fulfilment of the requirements for the degree Philosophiae Doctor (PHARMACEUTICS) at the POTCHEFSTROOM CAMPUS OF THE NORTH-WEST UNIVERSITY Supervisor: Prof. W. Liebenberg Co-supervisor: Dr. M.E. Physica 139 & 140B (1986) 240-245 North-Holland, Amsterdam POLYMORPHISM AND AMORPHISM AT HIGH PRESSURE A. ONODERA, Y. FUJII and S. SUGAI* Faculty of Engineering Science and Faculty of Science,* Osaka University, Toyonaka, Osaka 560, Japan Invited paper Polymorphic transition and crystalline-to-amorphous transformation at elevated pressure are described by … Polymorphism and amorphism at high pressure Onodera, A.; Fujii, Y.; Sugai, S. Abstract. Polymorphic transition and crystalline-to-amorphous transformation at … Polymorphism can potentially be found in any crystalline material containing polymers, minerals, and metals, and is related to allotropy, which refers to elemental solids. Abstract. The unprecedented polymorphism of the non-steroidal anti-inflammatory drug (NSAID) flufenamic acid (FFA) is described here.